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Abstract

Aim. The aim of this review study is to introduce the cardiac resynchronization therapy through biventricular pacing in treatment of heart failure.

Background. More than 22 million peoples worldwide suffer from congestive heart failure (CHF). As a result of the lack of synchronized contraction, both within and between the ventricles, blood moves through the heart and body at a slower rate. Heart failure impacts on almost all aspects of the quality of life of patients, particularly on mobility. Despite treatment advances such as lifestyle changes, medication and heart surgery, up to %40 of patients with CHF suffer an arrhythmia that further reduces the heart’s ability to beat properly. Cardiac Resynchronization Therapy (CRT) is a new, adjunctive and effective therapy that can relieve CHF symptoms by improving the synchronization of the heart’s contractions.

Findings. According to the studies, after BVP, heart contractility, and left ventricular ejection fraction and stroke volume increase, the incidence of cardiac arrhythmias decreases and some aspects of quality of life such as exercise tolerance improves.

Conclusion. Cardiac resynchronization therapy (CRT) along with other medical options can be safely performed and can relieve CHF symptoms by improving the coordination of the heart’s contractions.

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Aim. This study reviews the various studies conducted about using stem cells in the treatment of peripheral arterial disorders.

Background. Arterial disorders have affected approximately 8 to 12 million individuals in the united states and is associated with significant mortality morbidity and mortality. Critical limb ischemia (CLI) is the end stage of lower extremity peripheral arterial disease. The mainstay of therapy for severe ischemia is endovascular revascularization with the aim of improving blood flow to the affected limb. However, for 20 to 30 percent of patients with CLI that are not considered for endovascular revascularization stem cell therapy may be useful.

Method. In this review, after the searching out databases and electronic resources the latest and most relevant studies about the use of stem cell therapy were considered.

Findings. The studies have shown that stem cell therapy is useful for peripheral arterial disorders, especially for those patients who are not candidate for surgical treatment. It has been found that this method is more effective for patients with Buerger's disease than those with peripheral arterial disorders, and that intramuscular injection method is preferred to intra-arterial injection method. It has been shown that using stem cells derived from bone marrow is more effective and less costly than stem cells derived from peripheral blood. This method is not associated with significant side effects and well tolerated by patient.

Conclusion. Stem cell therapy is an effective and promising treatment strategy, especially in patients who are not candidate for endovascular surgery.

 

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Abstract
Aim. This study was conducted to determine the effect of education on quality of life in people with unstable angina in Qa'en, Iran.
Background. Cardiovascular diseases are the most prevalent and important cause of death all over the world, which affect the patients' quality of life. These diseases create many problems for patients and a lot of cost for the society.
Methods. This study was an experimental study with pretest-posttest design and control group which was conducted on 60 patients in the cardiac care unit Shohada hospital located in the city Qaen, Iran in 2015. The recruited patients were divided randomly into control and intervention group. During 3-6 sessions of face-to-face training (1-2 sessions per day) lasting between 15-20 minutes, screenshots (in PowerPoint software) were used and the participants questions were abswered. The quality of life of the patients in both groups were measured at two stages, before education (for intervention group) and one month later. The instruments were demographic and quality of life questionnaires (SF36). Data were analyzed in SPSS, version 20.
Findings. There were a statistically significant difference between the groups in terms of the mean scores of quality of life in the following dimensions: general health (p=0.02), physical function (p=0.003), role limitation due to physical health (p=0.05), energy fatigue (p=0.01), emotional well-being (0.004), pain (p=0.007), and total quality of life (p=0.02) .
Conclusion. Education can be a useful method for improving quality of life in people with unstable angina patients.

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Abstract
Aim. The aim of this study was to determine the relationship between quality of life and demographic characteristics of people with angina pectoris in Shohada Hospital in Qaen city, Iran in 2014.
Backgrounds. Cardiovascular disease is the most common cause of death in most countries around the world, including Iran, and also, it is the most important cause of disability. Cardiovascular disease is one of the most preventable non-communicable diseases. Quality of life in heart disease is associated with inappropriate changes, as several factors contribute to improving the quality of life of these patients..
Method. This cross-sectional correlational study was conducted on 240 individuals with angina pectoris in the CCU and Post-CCU wards of Shohada Qaen Hospital, Qaen, Iran, from April to December 2014. The sample were recruites by census method and the SF-36 tool was used to assess the quality of life. The questionnaire was completed by interviewing patients. Data were analyzed in SPSS-20, using Mann-Whitney and Kruskal-Wallis tests.
Findings. The mean score of total quality of life was 61.74±22.49, indicating good quality of life. The findings showed that the age was significantly related to the role disorder due to emotional health (P=0.034), energy/ fatigue (P=0.001) and general health (P=0.004) domains of quality of life. The gender was significantly related to the role disorder due to emotional health (P=0.008), energy/ fatigue (P=0.01), social function (P=0.003) and general health (P=0.04). The marital status was significantly related to the physical function (P=0.032), and energy/ fatigue (P=0.04). Finally, a statistically significant relationship was found of education level with energy/ fatigue (P=0.007) and general health (P=0.001).
Conclusion. The use of appropriate care approaches, including educational programs is suggested for people with angina pectoris in order to improve their quality of life.