Abstract
Aim. The purpose of this study was to examine the effect of Zero-balance (Z-Buf) ultrafiltration on arterial blood gases in patients undergoing coronary artery bypass graft surgery.
Background. Cardiopulmonary bypass can cause complications such as systemic inflammatory response syndrome, ischemic reperfusion injury, decreased cardiac output, and other related complications.
Method. This study was a randomized clinical trial study with control group. Seventy six patients undergoing coronary artery bypass grafting were selected through consecutive sampling method from early January 2016 to the end of June 2017. To allocate the participants into groups, randomized blocking method was used. Patients in the experimental group were connected to the cardiopulmonary bypass system and Zero-balance (Z-Buf) ultrafiltration. Arterial blood gases including BE, Pao2, Pco2, Tco2, PH, Lactate, and O2Sat were measured in the preoperative time, every half hour during the operation, immediately after the operation and 6 hours after transferring the patient to intensive care unit. The data were analyzed by descriptive and inferential statistics in SPSS Version 22.
Findings. The results showed that the changes in PCO2 in both groups were not statistically significant, but the changes in other arterial blood gas parameters (BE, Pao2, Tco2, PH, Lactate, O2Sat) were statistically significant in two groups (P<0.05). There were more changes in arterial blood gases in the control than the experimental group.
Conclusion. The use of Zero-balance ultrafiltration reduces changes in arterial blood gas parameters in patients with undergoing coronary artery bypass graft surgery. The use of this method by heart surgeons and perfusionists can reduces the incidence of clinical complications in these patients.