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Showing 2 results for Montaseri
Mohammad Montaseri, Fatemeh Bahramnezhad, Volume 12, Issue 1 (3-2023)
Abstract
Aim. The present study was conducted with the aim of reviewing the role of serum albumin in heart failure.
Background. Heart failure is a complex clinical syndrome that affects a large population worldwide yearly, and its mortality is even higher than that of many cancers. Although the identification of traditional risk factors has helped in primary prevention, the death rate due to this disease is still increasing. Identifying potential and modifiable risk factors that are not known yet seems necessary in this situation. Serum albumin has been known for many years as a strong prognostic biomarker in many pathological conditions. In recent years, studies have been conducted regarding the role of serum albumin in the prediction, prognosis and treatment of heart failure symptoms.
Method. This narrative study was conducted in 2023. For this purpose, the data bases, PubMed, Scopus, Web of Sciences, SID, MagIran were searched out with the keywords albumin, heart failure, diastolic failure, systolic failure, and a total of 30 articles were included in the study.
Findings. Hypoalbuminemia is a common finding in patients with heart failure, and among its main causes in heart failure are malnutrition, inflammation, lack of intestinal function, lack of kidney function, and liver disease. According to clinical and experimental evidence, hypoalbuminemia is related to fluid retention and exacerbation of pulmonary edema in these patients. Also, hypoalbuminemia can independently predict the onset of a new heart failure and can be measured as a prognostic factor of heart failure outcomes. However, there is still no evidence that directly shows the benefit of albumin injection in patients with heart failure.
Conclusion. Serum albumin can be measured as a modifiable risk factor and a prognostic factor in heart failure, but it is necessary to limit its use to cases where its effectiveness has been confirmed.
Mohammad Montaseri, Dr. Fatemeh Bahramnezhad, Volume 12, Issue 1 (3-2023)
Abstract
Abstract
Aim. This study was conducted with the aim of providing care solutions to manage the hemodynamic status of potential donors with brain death.
Background. Currently, organ transplantation is the treatment of choice for complete organ failure. The results of studies have shown that a significant percentage of potential donors with brain death organs are not usable for transplantation due to hemodynamic instability. Therefore, hemodynamic management in this category of donors plays an essential role in the donation process. Despite the studies, there are no strong evidences and recommendations about the management of hemodynamic stability of these patients. Therefore, in this review, evidence-based solutions have been tried to maintain the hemodynamic stability of these donors.
Method. In this review study, with library search and search in databases PubMed, Scopus, Web of Science, SID, and MagIran with the keywords organ donor management, brain death, hemodynamic care, organ donor, deceased donor, hemodynamic management, donation after neurological death, and cardiovascular management published in the period from 2009 to 2024. In addition, the Google Scholar search engine was also explored. A total of 20 articles were included in the literature review.
Findings. Maintaining proper organ perfusion and identifying clinical conditions that can be effectively treated are among the most important goals of hemodynamic management of these donors, and hemodynamic monitoring, serum therapy, use of cardiac drugs, and hormone therapy are among the most important. There are also studies that recommend serial echocardiography to identify reversible clinical conditions.
Conclusion. The high demand for organ transplantation, and despite the high number of brain deaths and sometimes consent for transplantation, only a small percentage of these people's organs are successfully transplanted. In order to preserve the transplanted organs, it is recommended to take proper and basic care of the patients with brain death. It is necessary for nurses, especially nurses in the intensive care unit, to be very careful in caring for patients with potential brain death.
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